Open House at the LCI core facility – 17th of September 2026

On the 17th of September, the LCI core facility will open its door to everyone interested in seeing what we have to offer.

There will be guided tours, multiple demos (confocal Ax, super resolution NSPARC, Light sheet and multiplexing with 7 colours), private demos where you can bring your own sample and a workshop where you can learn how to easily make article figures using OMERO.

Our facility will also get a new name which will be announced to all visitors. 😊

Details of the venue and schedule for the day can be found here.

Sebastian Hildebrandt-Human Embryo - Copy
Sebastian Hildebrandt

SeeDB-Live: Clearing live samples with BSA

Amazing talk at the ELMI in Coimbra!

Takeshi Imai presented SeeDB-Live, a new clearing technique for live samples. The refractive index is 1.363 and the technique works exceptionally well in loose tissues like brain but allows also 2 times deeper imaging in live organoids. They could even image calcium with multiphoton repeatedly over several months in brain of live mice!

The paper was just published in Nature.

FLASH-PAINT: nm resolution, fast and highly multiplexed!

Just heard this amazing Eurobioimaging talk by Florian Shueder from EFPL. They published FLASH-PAINT, an improved version of DNA-Paint.

FLASH-PAINT combined with fluorogenic probes, eraser oligos and EXCHANGE-PAINT has many advantages over DNA-PAINT:

    • It keeps the very high resolution of just a few nm.
    • It is very fast.
    • It enables imaging with a widefield system instead of in TIRF.
    • It enables high multiplexing (they demonstrate 12 rounds) without needing to wash.

They demonstrate 12-plex imaging with 25nm resolution in just 2h!

 

Free, online microscopy course by the LCI core facility

Dear all

Kindly forward to anyone who might be interested.

It is my pleasure to invite you to follow our free (no registration) online microscopy course.

The course schedule and Zoom link are found our course webpage.

The public program (everything in blue in the course schedule) starts next week on Thursday 22th of Jan and runs until the 13th of February.

Here is a selection of what we will talk about:

  • Optics and image formation,
  • How microscopes work
  • Objectives and refraction index
  • Cameras and detectors, Noise and background, Bit depth and saturation
  • Sample preparation, Immunostaining, Clearing
  • Resolution and contrast, Nyquist sampling, how to choose microscope settings
  • Data handling, how to make article figures, Requirements for image analysis, Colocalization, Ethics
  • Image processing and analysis

All lectures will be broadcasted live on Zoom, recorded then posted the same day on our Youtube channel.

The course syllabus with the Learning Objectives can be downloaded here.

Do not miss the kind testimonies on our course webpage! šŸ™‚

The LCI core facility team, Stockholm, Sweden

3D imaging symposium

Dear all

An interesting whole-day 3D imaging symposium at Scilife on the 4th of December. Many really inspiring talks! šŸ™‚

Flemingsberg science fun!

Do you want to know more about working at a Biotech companies? Meet the companies located on the Flemingsberg campus! Join the Flemingsberg Science breakfast meetings (in English) every wednesday in Novum.

High Speed Multiphoton Imaging of Dynamic Processes In Vivo at Stockholm University

Intravital people might be interested in this event at the Intravital Microscopy Stockholm University facility:

Clearing live samples!

A couple of super cool papers about transiently clearing live samples to obtain better images!

On Bioarxiv

In Science

The online LCI microscopy course: Microscopy: improve your imaging skills – from sample preparation to image analysis.

Dear all

It is my pleasure to invite you to follow, online, free of charge and without registration, the LCI facility microscopy course Microscopy: improve your imaging skills – from sample preparation to image analysis. The public program starts on Tuesday next week (28th of Jan) and runs until the 13th of February.

As usual, all lectures are broadcasted live on Zoom and posted on Youtube every day, for the benefit of our far-away colleagues.

The aim for this course is to improve the microscopy skills of students and researchers who have already used a microscope to acquire digital images of fluorescent samples but feel that more knowledge could help them.

Here is a selection of what we will talk about:

  • Optics and image formation,
  • How microscopes work
  • Objectives and refraction index
  • Cameras and detectors, Noise and background, Bit depth and saturation
  • Sample preparation, Immunostaining, Clearing
  • Resolution and contrast, Nyquist sampling, how to choose microscope settings
  • Data handling, how to make article figures, Requirements for image analysis, Colocalization, Ethics
  • Image processing and analysis

Check our course webpage to see the course schedule (Broadcasted activities are in blue) and the Zoom link. Here is a full description of the course.

Scroll down to read the kind testimonies of our dear students! šŸ™‚

We hope that you will enjoy the LCI facility online microscopy course!

Kindly forward to anyone who might be interested.

The LCI team

Correlative microscopy webinar

For those of you who are interested in Correlative microscopy where one overlays the data acquired from different imaging modalities, Zeiss organises a webinar about combining light microscopy, EM microscopy and Z ray data for very large samples.

Here is the link.

 

Follow us! :-)

Type your email address below to subscribe to our blog!