Remember that with passive clarity, you can make most tissues transparent in order to image them.
The challenge may be to get the antibody to penetrate fully if your tissue is very thick but clarity removes lipid so it also helps with antibody penetration. If your protein expresses a fluorescent protein, you skip this problem and clarity preserves fluorescence.
You can then mount your tissue and image it on our microscopes! 🙂 It’s magic!! 🙂